To apply this cumulative update package, you must be running SQL Server 2016 RTM. So it is pertinent for versions 13.0.1601.5 - 13.00.1708.0.
The build number of the cumulative update package is 13.0.2149.0. You may have to restart the computer after you apply this cumulative update package. The cumulative update package updates only those components currently installed.
This update contains ~150 updates. That’s great that Microsoft are being very respnsive to issues from the first general release. There are a lot of fixes to MDS, so if you use MDS you really cannot ignore this update.
As usual, make sure you deploy Cumulative Updates in test environments before deploying straight to production and that you apply the most recent build that you apply the most recent build.